Please contact your Administrator to change your authorization settings.
The World's Brightest Minds Always Innovate
At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities, state-of-the-art technologies, and extraordinary support for your research to ensure scientific progress is never halted from a lack of resources. At St. Jude, you will be part of a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve.
This is an exciting opportunity for a Research Operations Manager to join our Center for Advanced Genome Engineering (CAGE).
The CAGE has three missions:
1) facilitate investigator-initiated genome editing projects using CRISPR-Cas9
2) perform independent R&D to evaluate and develop new genome editing techniques
3) to assist the gene and cell therapy programs at St. Jude Children's Research Hospital.
The Shondra Pruett-Millerlaboratory offers a strong team-based environment where you will work collaboratively with other investigators across the institution to support their research needs and develop and improve genome engineering technologies.
In this position, you will lead the Custom CRISPR Library service. You will stay up to date on current CRISPR screening technologies and adapt and incorporate them into current workflows to aid St. Jude investigators with their research. Duties will also include designing, cloning, and analyzing CRISPR libraries designed for knockout, inhibition, and activation screens. You will help fellow team members with their own designs and analyses. Your experience will also be used for developing and implementing bioinformatic workflows which aid CAGE lab members in CRISPR design and NGS analysis.
Successful candidates should display competencies in the following areas:
- Understanding of and experience with molecular biology techniques including DNA and RNA extractions, PCR, and plasmid cloning
- In depth knowledge and experience with CRISPR screens and analysis
- Excellent verbal and written communication skills
- Creative and self-motivated
- Experience with programming in python or other coding language is a plus
- Experience with liquid handling robots a plus
- Comfortable in a Linux environment and working on a cluster
- Comfortable working independently and as part of a team
- Ability to prioritize work based on need
- Ability to track and execute multiple projects at once
- Experience with Next-Generation Sequencing analysis is a plus
- Coordinates all aspects of scientific operations of a department or shared resource(s). Ensures operations adhere to institutional, state and federal regulations. In coordination with departmental leadership, develops laboratory operating procedures. Participates in the development and monitoring of capital and operational budgets, the negotiation of new contracts and the renewal of existing contracts. May supervise staff. Contributes to the scientific direction of the laboratory in partnership with Principal Investigator
Job Responsibilities:
- Collaborates with leadership to implement and maintain departmental or shared resource policies and standard operating procedures to support efficient operations. Monitors operations and workflow to identify inefficiencies and works with leadership to develop corrective action. Works with leadership to develop quality control processes and procedures.
- May supervise staff
- Works with leadership and department staff to ensure effective and efficient use of space within the department and shared resource(s)
- Participates in the development of capital and operating budget. Implements mechanisms for monitoring expenses. Reviews and approves purchasing requests.
- Participates in the negotiation of new contracts and renewal of existing contracts. Ensures contractual requirements are met and collaborates with vendors to enhance operations.
- Participates in the design, construction, equipping of shared resource(s). Coordinates preventative maintenance and repair to ensure safe and efficient operation. Orders new and replacement equipment. Monitors and maintains inventory of supplies.
- Collaborates with leadership to implement and maintain compliance and safety policies and procedures. Leads group of senior scientific support staff to investigate and resolve in non-compliance issues.
- May lead multiple aspects of research projects and carry out laboratory experiments and determine whether additional or other tools or methods are required. May provide input regarding research protocols and experiments.
- Performs other duties as assigned to meet the goals and objectives of the department and institution
- Maintains regular and predictable attendance.
Minimum Education and/or Training:
- Bachelor's degree is required
Minimum Experience:
- Seven (7) years of relevant post-degree work experience is required
- Five (5) years of relevant post-degree work experience is required with a Master's degree
- Three (3) years of relevant post-degree work experience is required with a PhD
- Leadership or supervisory experience is required
Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Research Operations Manager in St. Jude's Center for Advanced Genome Engineering.Explore our exceptional benefits!
Diversity, Equity and Inclusion
St. Jude Children's Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world-regardless of race, religion or a family's ability to pay. Learn more about our history and commitment.
Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital's roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
St. Jude Children's Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, sexual orientation, gender identity, transgender status, age, religion, disability, veteran's status or disabled veteran's status with respect to employment opportunities. All qualified applicants will be considered for employment. St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.